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Importantly, there was heterogeneity between agents: liraglutide (3.0 mg weekly and 1.8 mg daily) achieved weight loss without significant lean mass reduction, whereas tirzepatide (15 mg weekly) and semaglutide (2.4 mg weekly) were least effective in preserving lean mass [22]

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This is a matter to approach with great caution

However, a critical distinction exists between synthetic GH therapy and sermorelin treatment

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