2023 Warning added to Effexor XR labeling regarding the increased risk of postpartum hemorrhage 2021 The FDA suggested a label change regarding sexual dysfunction for all SNRIs 2007 Black box warning about suicide risk was expanded to recognize that depression is linked to a risk of suicide 2006 Risk of serotonin syndrome was added to the labeling Wyeth discontinues Effexor 2005 The FDA required the inclusion of warnings about the possible impacts of certain antidepressants on newborns whose mothers took these types of medications, including Effexor 2004 Black box warning added about the increased risk of suicide in children and adolescents 2000 Labeling change warning of discontinuation syndrome 1997 Effexor XR was approved by the FDA 1993 Effexor was approved by the FDA Effexor Lawsuits Multiple lawsuits were filed against Wyeth and Pfizer, claiming that Wyeth failed to warn pregnant women about the risk of birth defects when taking Effexor

Some individuals notice subtle improvements within 24 weeks
1 See TABLE 3 for common patient-reported barriers to CPAP therapy and potential management strategies
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