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380 Firstly, the expression of GLP-1R is enhanced in the inflamed muscle fibers under pathological conditions, revealing the critical role of GLP-1R in regulating the muscles response to inflammation

Any peptide with incorrect sequence or modified residues may have substantially different receptor binding profiles

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So far, weve put the spotlight on Wegovy and Saxenda, but other GLP-1s are FDA-approved for type 2 diabetes but are also used off-label for the treatment of overweight and obesity