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This difference in mechanism is what makes the combination potentially valuable

Signs might include itching, hives, or difficulty breathing

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Common side effects may include skin irritation, itchiness, or mild swelling at the injection site

The research shows weight loss of 10 to 12 percent with cagrilintide alone, and when combined with semaglutide in the CagriSema protocol , results exceed 22 percent body weight reduction over 68 weeks