10.2337/db16-1009 Summary Keywords GLP-1 receptor agonist, molecular mechanisms, gut microbiota, multi-organ protection, therapeutic repurposing Citation Gong B, Li C, Shi Z, Wang F, Dai R, Chen G and Su H (2025) GLP-1 receptor agonists: exploration of transformation from metabolic regulation to multi-organ therapy
doi: 10.1002/cmdc.201200409 117 LennoxR.PorterD
In this architecture, two metal ions create a binuclear pore structure, and the third ion is located at an egress site facing the cytoplasm
Use for 48 weeks for optimal tissue support and recovery outcomes
The major trials treated GLP-1s as long term, chronic therapies, with benefits maintained only while the medication was continued
Local injection may provide psychological benefit but no convincing evidence for superior outcomes