Potential Side Effects and Limited Human Data While preclinical studies have not shown significant toxicity at standard doses, the research in humans is still in its early stages
Any animal-model protocol should include defined humane endpoints, veterinary oversight, and IACUC or equivalent ethics-committee approval before initiation
Without suitable levels of B12, symptoms of a deficiency, such as weakness, weight loss, and confusion, may occur in people with UC
These body composition changes occurred without any measured change in food intake meaning the weight loss was driven by metabolic changes rather than appetite suppression
Intrauterine growth retardation and consequences for endocrine and cardiovascular diseases in adult life: Does insulin-like growth factor-I play a role
They support red blood cell production, DNA synthesis, and normal nerve function when deficiency is present