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Some patients report mild diarrhoea, nausea, or headache following administration, though these symptoms are usually transient

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For instance, in one 1960s study of intravenous NAD+ for addiction, patients who received a fast IV drip experienced immediate headache and shortness of breath, whereas those given the same dose at a slower drip rate (under approximately 35 drops/min) had no distress

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The injections are generally well-tolerated

Gut and Vascular Integrity: BPC-157 may help support gastrointestinal tissue integrity, endothelial function, and vascular repair