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doi: 10.1074/jbc.272.10.6663

Side effects of GLP-1 receptor agonists (such as Mounjaro and Wegovy) are divided into those that can be monitored and those that require immediate medical attention

For example, long-acting amylin analogues are in various stages of clinical development (Cagrilintide, Novo Nordisk

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However, notably, dietary L-carnitine significantly increased the mRNA expression of mTOR in the liver in the feeding state

This is consistent with findings from the SUSTAIN-6 and PIONEER trials, which reported reductions in major adverse cardiovascular events (MACE) with semaglutide use