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Similarly, interrupted use was associated with increased MACE risk, with IRRs of 1.12 for one year and 1.16 for two years of interruption, with effect sizes differing modestly depending on prior treatment duration

Active ingredients: Contrave contains two active ingredients: naltrexone (an opioid antagonist) and bupropion (an antidepressant)

For charge state z = 2, the MS isolation window was set at 1.2