Medications sold under brand names like Ozempic, Wegovy, and Saxenda have become famous for their weight-loss benefits, but that only scratches the surface of what these injections are potentially capable of
Additional research by Stanley and colleagues showed that tesamorelin reduced hepatic (liver) fat by approximately 37% in individuals with fatty liver disease, making it one of the few compounds that addresses both visceral adiposity and its downstream consequence of liver fat accumulation
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Brough, R
Direct mechanisms may involve GLP-1 receptor activation on vascular endothelial cells, whilst indirect effects result from weight loss, improved glycaemic control, and reduced visceral adiposity, all of which independently lower inflammatory burden
[1] The Summary of Product Characteristics also states that reduced food intake with tirzepatide contributes to body-weight loss and that tirzepatide delays gastric emptying, although this delay diminishes over time