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Its deficiency can lead to nerve damage and various neurological symptoms

DOI: 10.1080/15563650.2019.1606432 Aroda VR et al, "Long-term metformin use and vitamin B12 deficiency in the Diabetes Prevention Program Outcomes Study." Journal of Clinical Endocrinology and Metabolism, Feb

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In cases of pernicious anemia, as an appetite stimulant when suspected vitamin deficiency, to maintain the proper functioning of the nervous system in states of tension, it is recommended when sudden changes in environment, food or temperature occur

Precautions : Inform your doctor if you have Lebers disease, liver/kidney issues , or take other medications (may affect B12 absorption)