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Thats why results are gradual and systemic

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GSTs gene polymorphisms and correlation to diseases GSTs are representedand expressed with unique patterns in each organin the human genome by multiple genes that are located in class-specific clusters on different chromosomes 31,32,33

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Judge A, Dodd MS

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In theory, reduced paracetamol sulphation due to reduced sulphotransferase activity could lead to increased paracetamol oxidation to NAPQI

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Everything flows from there

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