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Cortisol can impair bone microstructure via multiple mechanisms, including modifying bone cell function, regulating inflammatory cytokines, and influencing calcium metabolism (69), among others

NNMT is a metabolic enzyme widely distributed in the cytoplasm of human cells

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Derived from the p53 tumor-suppressor protein, PNC-27 exhibits a unique binding affinity for the MDM-2 protein found in the membranes of cancer cells