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Cortisol and Prolactin Considerations Unlike ipamorelin, which selectively releases GH without affecting other pituitary hormones, GHRP-6 has a broader activation profile

This effect was suggested to be due to multiple mechanisms, including alteration of the bile acid pool, changes in microbiota composition, improvement of hepatic glucose metabolism, and increased release of incretin hormones (204, 205)

Improvements in blood glucose, cholesterol and blood pressure reverse within ~18 months after GLP-1s, versus an estimated ~5 years after behavioural programmes

Oxidative stress is enhanced because of the accumulation of H 2 O 2

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If 30-45 minutes isnt feasible, start with 10-15 minutes