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Proteolytic enzymes such as elastase, proteinase-3, cathepsin G, cathepsin B and matrix metalloproteinases (MMP) released by neutrophils cause damage to elastic lung tissue (Mehta et al

However, its important to note that these are observational insights and anecdotal experiences rather than findings from large-scale, peer-reviewed clinical trials

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This energy-intensive process occurs in the mitochondria, where the increased metabolic activity required to produce ATP inherently generates ROS as a byproduct of the ETC (electron transport chain) [84]

Another study in ALS also indicates an important role in neurodegeneration (Maor-Nof et al., 2021)

Probiotics may help restore gut balance