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doi:10.1016/j.mayocpiqo.2019.03.002

These medications work by reducing appetite, promoting fullness, and helping you eat less without extreme dieting or exercise

Older adults, people on stimulants or sympathomimetics, and those who become dehydrated from reduced intake or severe gastrointestinal side effects are more likely to show exaggerated heart rate responses

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Tirzepatide works through whats known as incretin biology, which is our hormonal response system to control glucose levels and appetite following meals