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Modelling human liver fibrosis in the context of non-alcoholic steatohepatitis using a microphysiological system

A consistent pattern emerges in phenotypes with a high metabolic burden, such as obesity and IGT or pre-diabetes, improvements in fasting glucose, OGTT curves, and HbA1c are more pronounced, with some subjects even reverting from IGT to normoglycemia

Ferrali et al

& Ladenstein, R