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[DOI] [PubMed] [Google Scholar] 23.Zhang M., Yang B., Ren T., Wang X., Chen H., Lu C., Wu C., Pan X., Peng T

This effect is specific to oral oestrogen and is largely absent with transdermal oestradiol, which avoids hepatic first-pass exposure

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However, evidence specifically addressing their use in SIH and SID remains limited, underscoring the need for focussed investigation in this patient population