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The most significant long-term concern is muscle loss with rapid weight loss, which is why proper nutritional support throughout treatment is essential

GLP-1 drugs have captured the attention of providers, patients and nonpatients alike because of amplified media coverage and soaring demand

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95% CI 1.05 to 1.44), with longer treatment periods associated with a greater risk [90]

J Neurol 270(2):851863 Wharton S et al (2022) Gastrointestinal tolerability of once-weekly semaglutide 2.4 mg in adults with overweight or obesity, and the relationship between gastrointestinal adverse events and weight loss

Dual and Triple Agonists: The next generation of medications, such as Tirzepatide (which targets both GLP-1 and GIP receptors), are already demonstrating even greater efficacy for weight loss and blood sugar control