doi: 10.1111/j.1365-2044.2007.05370.x
Glutathione binds to free radicals via sulfhydryl groups, thereby accelerating their excretion
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Through activation of the Nrf2antioxidant response element (ARE) signaling axis, GSH upregulates cytoprotective enzymes such as heme oxygenase-1, glutathione peroxidase, and NAD(P)H quinone oxidoreductase-1, thereby enhancing cellular resistance to oxidative injury [10]
Nonetheless, there is now convincing evidence that the increase in glucose-stimulated insulin secretion following administration of exogenously applied GIP is mediated by direct activation of GIP receptors (GIPR) expressed on pancreatic -cells (15,27)