6X18: Zhang X, Belousoff MJ, Zhao P, Kooistra AJ, Truong TT, Ang SY, Underwood CR, Egebjerg T, enel P, Stewart GD, Liang YL, Glukhova A, Venugopal H, Christopoulos A, Furness SGB, Miller LJ, Reedtz-Runge S, Langmead CJ, Gloriam DE, Danev R, Sexton PM, Wootten D
In another trial, patients who reduced their Zepbound dose to a lower 5 mg maintenance dose also preserved much of their earlier weight reduction compared with those who stopped treatment entirely
They are not meant for purely cosmetic use or short-term crash dieting
2023 Aug 5;402(10400):472-483.
What this means practically is that your choice of morning versus evening should be driven by side effect management and routine compatibility, not by chasing marginally different blood levels
Friday: The FDA Drops the Hammer On February 6th, one day after the HIMS launch, FDA Commissioner Martin Makary issued a statement that may be the most consequential regulatory action in the compounded GLP-1 saga to date