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Glutathione and Mitochondrial Health Glutathione is a tri-peptide made up of the three amino acids, L-cysteine, L-glutamic acid, and glycine

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Interestingly, GSAAT(WT), GSAAT(C138S) and GSAAT(C396S) lines were still markedly redox responsive, and exhibited up to 20% higher enzyme activity when supplied with DTT relative to the UT control conditions, while the two gsa2 lines expressing GSAAT(C168S) and GSAAT(C190S) resulted only in 9% and 2% increased GSAAT activity upon addition of DTT to the extracts ( Supplementary Figure 3E )

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When applied to epilepsy, NMR-based metabolomics can help uncover specific biochemical patterns associated with disease state and seizure activity, potentially facilitating better diagnostic and therapeutic strategies