This molecule is used as a key cofactor for hundreds of cellular redox reactions and serves as the mandatory substrate for NAD + -consuming enzymes that are critical players in the control of DNA repair (i.e., PARPs) or modulation of cellular energetic status, especially the activation of oxidative metabolism and stress resistance in mitochondria in various physiological or pathological conditions (i.e., SIRTs) [21, 71]
NAD vs Glutathione: Key Functional Differences Image Source: EMBO Press NAD and glutathione work as two distinct biochemical powerhouses at the molecular level
Prepare the Glutathione Solution: Wash your hands thoroughly before handling any equipment or medications
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doi: 10.1080/09540105.2021.2022604 35 IkonenE
2.8 Elevated plus maze test The EPM test was implemented to investigate anxiety-like behavior in rodents, following the protocol delineated by Handley and Mithani (Guo et al., 2023)