Nature 628 , 162170 (2024)
Wegovy pill The FDA-approved Wegovy tablet is indicated for chronic weight management in adults with obesity, or adults with overweight plus at least one weight-related condition, alongside diet and physical activity
tirzepatide (LY3298176, picture from literature: PMID-31686879) SURPASS-4 is an open-label global trial, in 2002 cases of increased cardiovascular (CV) risk, have received 1-3 oral hypoglycemic drugs (metformin, sulfonylurea, SGLT2 inhibitors) treatment but blood sugar levels are controlled It was carried out in adults with poor type 2 diabetes, and the efficacy and safety of three doses of tirzepatide (5mg, 10mg, 15mg) and titrated insulin glargine were evaluated
About 91% of participants maintained their weight loss through the study period without significant regain or reduced effectiveness
The consistent increase under professional supervision helps patients build tolerance while carefully monitoring progress, making adjustments as needed based on individual reactions
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