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The excess -glutamyl-cysteine is converted into 5-oxoproline, an earlier intermediate in the cycle [810]
doi:10.1124/dmd.116.070615 6
Edited by Professor Alessandro Finazzi-Agr Supplementary information Rights and permissions Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made
Gene expression levels were standardized using the z score method, and cluster analysis of DEGs in key pathways was performed using the pheatmap R package [33] based on standardized FPKM values
Study done by van Eenige R, et al