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Callaghan BC, Xia R, Reynolds E, Banerjee M, Rothberg AE, Burant CF, et al

doi: 10.1016/j.carbpol.2012.12.006

Nicotinamide N-methyltransferase and liver diseases

While hypoperfusion likely plays a role, oxidative stress and subsequent renal tissue damage from reactive oxygen species occurs due to both ischemia-reperfusion injury and activation of inflammatory cascades when blood is exposed to the CPB circuit [37]