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A: Common side effects include nausea, vomiting, diarrhea, and injection site reactions

Dose-proportionality of oral thioctic acid--coincidence of assessments via pooled plasma and individual data

Xu J, Li T, Wu H, Xu T

The TRIUMPH-4 result of 28.7% at 68 weeks exceeded the Phase 2 result, suggesting the effect strengthens with longer treatment

These crystals physically tear apart the protein structure

Taken together, these biochemical results suggest that ultraviolet irradiation of the skin causes changes compatible with aging that manifest as a reduction in the content of pro-collagen type 1, elastin and sulfated GAGs, as well as an increase in MMP1 activity, and the CG treatment reverses these changes by increasing the levels of these extracellular matrix components, except for MMP1 activity, which can be attributed to its rejuvenating effect