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Autocrine VEGFR1 and VEGFR2 signaling promotes survival in human glioblastoma models in vitro and in vivo

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Of interest, our experiments administering G49 to mice lacking hepatocyte FGF21 in which Fgf21 expression was found elevated upon G49 treatment revealed an extra-hepatic contribution to plasma FGF21 by eWAT and iWAT as reported 59