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Smalley et al [9] used a discontinuous gradient of 20%, 26% and 32% OptiPrep for purification of Rickettsia australis but did not give any more detailed information

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[DOI] [PubMed] [Google Scholar] 41.Seal CE, Zammit R, Scott P, Flowers TJ, Kranner I

In 2015, an FDA Advisory Committee voted that drug efficacy had not been demonstrated