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PMID 37237960

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The master cell cycle checkpoint kinase ATM increases 80% in breast cancer cells and 120% in prostate cells

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This is the same mechanism targeted by topical brightening agents, delivered systemically instead, and the effect is best understood as a gradual, cumulative brightening support across a series rather than an overnight change

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AFM can measure the stiffness and viscoelastic properties of individual collagen fibrils and other ECM components, providing detailed information about how molecular structure relates to mechanical function

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Controlling the role of BPC 157 likely involves its particular interaction with the major systems involved in wound healing, such as the NO-system (counteracted harmful events, arising from either NO-blockade or NOS-substrate application) (Sikiric et al., 2014) and the prostaglandins system (i.e., large extent of the counteracted NSAIDs toxicity (Sikiric et al., 2013) as well as counteracted developing and already formed adjuvant arthritis in rats (Sikiric et al., 1997c))

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