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Senescent cells stop producing collagen, begin secreting enzymes that degrade existing collagen and elastin, and create a local inflammatory environment that accelerates surrounding tissue aging

Future research will inform optimal dosages and formulations for clinical trials

Epub 2020 Jan 20

This coding system makes it easier to correctly sort diagnoses, write clinical notes, and charge for medical services

A previous study found that an increased stable form of erastin, IKE, has antitumor activity in a mouse model of diffuse large B-cell lymphoma (DLBCL), which suggests that IKE is a viable therapeutic option for DLBCL