Its job is to tell the brain you are full, slow how fast the stomach empties so that fullness lasts, and steady post-meal blood sugar
You can hear the full audio version of this article created so you can absorb this story in the way that feels easiest and most supportive for you
These numbers substantially exceed what semaglutide delivers at its maximum dose, which is exactly what you would expect from a medication hitting two receptor systems instead of one
J Diabetes Complications 34(12):107723 Kellaher C (2022) Eli Lillys Tirzepatide Meets Main Endpoints in Phase 3 Obesity Study, MarketWatch
However, most studies have focused on specific patient subgroups, limiting the generalizability of the findings to the broader population of individuals with obesity
In fact, it seems to be the reverse of it: insulin resistance makes it very difficult to lose weight, while GLP-1 receptor antagonism makes it very difficult to gain weight