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(B) overall structure of the mastermind-like transcriptional coactivator 1 (MAML1):ankyrin (ANK):CSL:DNA complex
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While a high carbohydrate meal can lead to an increase in oxidative stress, and caloric intake of lipids that exceeds energy expenditure leads to high production of ROS, essential fatty acids (EFAs) of the omega-3 family, in contrast to other lipids, play a defensive role from oxidative stress (270, 271) Eating fibre-rich foods may protect against oxidative stress, slightly improving the indices of inflammation and oxidative stress (272)
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TUMORS Rare causes of hyperthyroidism include metastatic thyroid cancer, ovarian tumors that produce thyroid hormone (struma ovarii), trophoblastic tumors that produce human chorionic gonadotrophin and activate highly sensitive TSH receptors, and TSH-secreting pituitary tumors
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