Autism, neurodevelopmental disorder is one of the genetic defects that can occur, together with other important factors
These include lack of awareness of health care professionals about prompt diagnosis and adequate management of hyperammonemia, strained communication between physicians at primary, secondary, and tertiary hospitals, and lack of knowledge and availability of the diagnostic tools and medications required in the acute management of hyperammonemia
In addition, the carnitine pool influences the metabolic process of branched-chain amino acids (BCAAs)
Their toxicity often stems from their ability to bioaccumulate and disrupt cellular functions by binding to proteins and enzymes
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Immunohistochemical staining supports the association between 8-OH-dG and fibroids, as significantly higher levels are seen in human fibroid biopsy tissue compared to normal myometrial tissue [63]