Estrogen or more precisely, the lack of it during menopause, when the ovaries dramatically reduce their output may impact how GLP-1s work
Retatrutide's glucagon arm produces more nausea than pure GLP-1 compounds, so stabilizing it first makes it much easier to tell where any new symptom is coming from
Only 3.3% of STEP UP participants stopped treatment because of side effects
DOI: Published online: July 1, 2025 Division of Endocrinology and Metabolism, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea Corresponding author: Hye Jin Yoo Division of Endocrinology and Metabolism, Department of Internal Medicine, Korea University Guro Hospital, Korea University College of Medicine, 148 Gurodong-ro, Guro-gu, Seoul 08308, Korea E-mail: [email protected] Copyright 2025 Korean Diabetes Association This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited
A few specific peptides need a mildly acidic solvent
Front Aging Neurosci (2021) 13:741923