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However, as an increasing body of evidence demonstrates that paracrine interactions between alpha-cells and beta-cells are essential for the coordination of insulin secretion in vivo , it follows, therefore, that this paracrine crosstalk is also essential for the beneficial metabolic effects of pharmaceutical agents in vivo

Theyre fundamentally different classes of compounds with different mechanisms, different effects, and different risk profiles

So which one actually deserves your attention

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J Agric Sci

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