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Concluding Remarks SP used for oral tissue regeneration offer several advantages including increased specificity, small size, excellent safety, less immunogenicity, great stability, low risk of systemic toxicity, and low cost

Theyre also heavily promoted in biohacking communities and by clinics that specialize in longevity optimization. Some celebrities and influencers in the wellness space have referenced NAD+ drips as part of their routine, which contributes to the trends visibility

Furthermore, most of the studies focused on immunohistochemical and gene expression outcomes

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In February 2025, Novo Nordisk also filed for regulatory approval in the EU, followed by regulatory submission in Japan in May 2025