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Protect against NSAID- and alcohol-induced mucosal injury

Integrative physiology of transcellular and paracellular intestinal absorption

As discussed in this review, many gut-brain peptides and their receptors are expressed within corticostriatal-limbic circuitry

Those taking SGLT2 inhibitors alongside GLP-1/GIP medications face additional risks, including increased urination and potential for euglycemic diabetic ketoacidosis if severely dehydrated

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Genetic variants in GLP1R (rs6923761), GIPR (rs1800437), FTO (rs9939609), and MC4R (rs17782313) influence appetite regulation, metabolic rate, and medication response