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The specific order of these 15 amino acids is Gly-Glu-Pro-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val

Moreover, cancer cells carrying mutations of succinate dehydrogenase, fumarate hydrolase or isocitrate dehydrogenase accumulate -KG competitors including succinate, fumarate and 2-hydroxyglutarate, respectively 43,49,50

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