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Uh, they are active for a longer period of time where they have an antioxidant and anti-inflammatory effect that lasts, far beyond what that little intermittent stress was and helps you deal with the stress of aging, normal metabolism, normal inflammatory pathways being activated

Thyroid hormones, serotonin and mood: of synergy and significance in the adult brain

American journal of physiology Cell physiology

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Yes, many people choose to cycle their supplements