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2.4 mg once weekly is the labeled maximum for weight management

Health technology assessment bodies require demonstration of value beyond statistical efficacy, including durability of effect, quality-of-life improvement, and reduction in downstream healthcare costs

Whats more, they are not recommended for patients with certain health conditions, including a history of medullary thyroid cancer

A randomized clinical trial published in JAMA Psychiatry demonstrated reduced alcohol craving and consumption among participants receiving semaglutide, with secondary reductions in cigarette use among smokers (Hendershot et al., 2024)

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This research shows how targeted, early-stage support can have an outsized impact, Kucenas said