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Unlike paracrine FGFs that act at the tissue level, FGF21 circulates systemically and requires the -Klotho co-receptor in complex with FGFR1c to mediate its effects, conferring tissue specificity

Soluble fiber supplements (like psyllium) may help bulk stools once acute symptoms improve

Combination therapy with BPTES nanoparticles and metformin targets the metabolic heterogeneity of pancreatic cancer

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It is important to ask the right questions and understand what to expect during medical consultations