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Beyond lipid metabolism, the GLP-1 RAs also shown critical anti-inflammatory and antioxidant effects, collectively positioning these GLP-1 RAs as a leading pharmacotherapy for MASLD (Chen et al., 2025
Randomised trial comparing weight loss through lifestyle and GLP-1 receptor agonist therapy in people with MASLD
GLP-1s may no longer only useful for weight loss and diabetes they are critical for building metabolic resilience and reducing inflammation, making them a powerful component of whole-person, lasting health
Supporting 25% of novel drug approvals* across FDA and EMA Signant Health's technology and services have supported a quarter of all regulatory authorizations for new active substances in their first indications across major global markets
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