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Replacing fluids and electrolytes helps maintain blood volume and circulation, supports temperature regulation, and keeps nerves and muscles firing smoothly, so long sessions and hot days feel more manageable

Remarkably, beneficial effects have been observed across this 100-fold range, suggesting a wide therapeutic window where smaller doses remain biologically active

[DOI] [PubMed] [Google Scholar] 97.Hoffmeyer R.E., Singh S.P., Doonan C.J., Ross A.R., Hughes R.J., Pickering I.J., George G.N

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Chronic adolescent exposure to 9-tetrahydrocannabinol decreases NMDA current and extrasynaptic plasmalemmal density of NMDA GluN1 subunits in the prelimbic cortex of adult male mice

doi: 10.1080/15548627.2015.1037061 30 MaQ