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Those are two very different things

High Oxygen Consumption: The brain consumes about 20% of the body's oxygen despite comprising only 2% of body weight, leading to a higher rate of ROS production in neurons

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Rapid, significant weight loss, especially when it occurs quickly, leads to loss of subdermal facial fat

Dutton DJ, Fyie K, Faris P, Brunel L, Emery JH

The review summarizes findings from various clinical trials, particularly the PIONEER trials, which demonstrated that oral semaglutide effectively lowers blood glucose levels and aids in weight loss