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In contrast, another study in rats demonstrated that acute injection of the GLP-1R agonist exendin-4 (Ex-4) increases baseline glucose levels in rats which is due to the activation of the sympathetic nervous system (Perez-Tilve et al., 2010)
Nat Rev Dis Primers (2020) 6(1):7
Continued daily dosing maintains elevated lipolytic activity in adipose tissue