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10.1016/0304-3940(92)90152-w Neurosci

doi: 10.1080/87559129.2023.2230268 282 CuiSGuJLiuXLiDMaoBZhangHet al

3.2 Curcumin: potential risks and challenges Despite numerous studies highlighting the potential benefits of CUR, certain adverse effects and toxicities have been reported, particularly at high doses or with prolonged use

The peptide reaches dermal fibroblasts and follicular tissue at concentrations sufficient to stimulate collagen production and hair growth

The high-mobility group box-1 (HMGB1) protein is a pro-inflammatory nuclear protein that is passively released and targets Toll-like receptors (TLR) to alert the immune system of dying cells (Lotze and Tracey 2005

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