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As weight loss progresses and sleep apnea potentially improves, repeat sleep studies (polysomnography or home sleep apnea testing) should be performed to objectively assess whether CPAP settings require adjustment or whether therapy can be discontinued

Ristow M, Zarse K, Oberbach A, Klting N, Birringer M, et al: Antioxidants prevent health-promoting effects of physical exercise in humans

Nat Clin Pract Neurol 2009;5:8292

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Cholesterol and its biosynthetic intermediates, including 7-dehydrocholesterol, have been implicated in ferroptosis suppression in multiple studies through their ability to limit membrane lipid peroxidation and act as radical-trapping antioxidants 22,38,62,63,64

PlexusDx personalized protocols use a dose titration approach where your healthcare provider may recommend stepping up from 0.25 mg to 0.5 mg to 1 mg to 2.4 mg over successive weeks