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Description

SETD2 catalyzes the interaction of histone H3 lysine 36 trimethylation (H3K36me3) with the ferrochelatase promoter, and knockdown of SETD2 significantly increases erastin sensitivity and promotes ferroptosis in ccRCC (149)

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[14] have demonstrated that disruption of a fungal Zn(II) 2 -Cys(6) binuclear cluster domain transcription factor ( gliZ ) results in the complete inhibition of all gliotoxin cluster gene expression and effective diminution of gliotoxin production [14]

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Two transcriptomic analyses of ivermectin-resistant ticks compared to susceptible ticks found that cytochrome P450 had an important role in ivermectin resistance in ticks (Ruiz-May et al

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Gutierrez 2011

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All these characteristics are closely related to ferroptosis

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