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Aliment Pharmacol Ther 2001

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Additionally, NSW affects methylation of immune-modulatory genes and human endogenous retroviral elements such as ERVFRD-1, HERV-L, and HERV-P, indicating combined effects of circadian and metabolic stressors on immune epigenetic regulation 234

The gastrointestinal effects are considered a class effect of GLP-1 receptor agonists

Of note, development of new compounds with longer half-life and higher stability will decrease the number of injections and certainly improve patients acceptance of treatment

Telogen effluvium from rapid metabolic shifts The most common cause of GLP-1 related hair loss is telogen effluvium, a condition where a large percentage of hair follicles simultaneously shift from the anagen (growth) phase to the telogen (resting) phase